Showing posts with label children. Show all posts
Showing posts with label children. Show all posts

Monday, November 3, 2014

Children with dyslexia might also be having difficulties with social skills

A reluctance to do any reading may be a classic sign of dyslexia, but there may be other tell-tale signs that can raise a parent's concern according to Joanna Dunton of Bangor University's Miles Dyslexia Centre.

Speaking ahead of Dyslexia Awareness Week, (3- 9 November) Language Therapist Jo Dunton explained that children with dyslexia might be having difficulties with reading, spelling and writing, but also with social skills, and with other seemingly unrelated areas.

"It could be that a dyslexic child may be particularly prone to forgetting things or being rather disorganised," explained Jo Dunton.

"Because of the challenges facing them, children with dyslexia may appear withdrawn or lose interest in school work, or might want to avoid going to school and, research has shown, could often be bullied or socially isolated due to their difficulties."

"These differences can lead to low self-esteem, especially if the child doesn't understand why they're having to struggle to do things that other children seem to be able to achieve with ease."

"Recognising the problem can be extremely helpful, as can setting things in place to help the dyslexic child overcome the particular difficulties facing them."

However dyslexia is not all negative, many people with dyslexia have great spatial or 3D awareness, and many go on to be engineers.

Places such as the spy HQ GCHQ have dyslexics ranking among their staff as does space agency NASA, so the sky's the limit!

If you think your child may be facing difficulties with reading, writing or any educationally related problem, then the first port of call should be the school" she told reporters.

"However, here at the Miles Dyslexia Centre we're always willing to speak with parents and advise them and can provide consultation sessions for parents and children."

Jo's Top Tips for Parents:

  • Talk to your child - discuss their day or their feelings. Vocabulary has been shown to have a major impact on developing literacy skills.
  • Look at the whole person rather than focus on your child's difficulties. Encourage then to get involved with things that they are good at as this will help build self-esteem.
  • Don't let homework become a battle ground. Little and often is more effective, reading one page or practising one word is better than nothing at all.
  • Spelling practice can be done with a whiteboard or with plastic letters. Try to find a way to make it fun.
  • Reading does not always have to be from a book. Perhaps use sets of word cards to make sentences, play matching or pairs games. Don't let your child view it as a chore that has to be done.
  • Out shopping- ask your child to read out the shopping list or the signs around the store. We are surrounded by words, use them as resources.
  • Talk to the school about any concerns you may have. Working together with the school can lead to a more coordinated response to any difficulties.
  • Self-organisation can be a key difficulty leading to forgotten books, kit, pens etc. Encourage your child to develop a routine. Is it swimming tomorrow? – Get the kit ready tonight!
  • Encourage the use of memory joggers such as checklists, 'to do' lists or school planners. Perhaps a large chalkboard or whiteboard could be used as a family planner.
  • Remember reading and spelling are skills, and, like any skill, they need lots of regular practice. Footballers, swimmers and tennis stars also have to work hard to improve their skills!

Thursday, October 9, 2014

Addressing Whining and unwanted behaviour in young children

Whining: That Voice!

Whining is high on the list of childhood behaviours that are really, really obnoxious to parents.

Some kids have developed this strategy into a dramatic art form, and there are a few youngsters who definitively deserve academy awards for their performances!

Many parents dread saying "No" to their kids, or not giving the children what they want, simply because of the threat of the whining that will result.

As aggravating as whining is, it can be managed. That management starts with a good understanding of where the behaviour comes from, followed by the use of a Calm, Decisive and Consistent strategy to address it.

What Causes Whining? 
You don't have to search far to discover the causes of whining. The answer to the question goes something like this.

Good parents have two sides to them, a warm, loving side and a demanding dominant side. To the child, the warm, loving part of parenting involves fun, affection and good times.

The demanding part involves learning to follow rules, acquiring skills and, basically, growing up and accepting responsibility for your actions.

The warm side of parenting is more friendly; the demanding side is more challenging.

You generally won't run into whining from your children when you are operating in the warm parenting mode.

However, you will run into whining when you are coming from the demanding side of the parenting equation.

Being demanding is a big part of your job as a parent, but it can create frustration and inappropriate reactions from your youngsters.

When you ask or demand a behaviour from a child, they have two choices: They can bite the bullet and cooperate or they can do what we call "test and manipulate."

Whining is a form of testing and manipulation.

Adults Reinforce Whining?
What makes whining work for kids?

Whining continues, and gets worse when mums, dads, grandparents or teachers do any of the following:

1. See whining as abnormal, horrible behaviour.
2. Feel angry or guilty when the kids complain.
3. Talk, argue, yell or whine back when the kids moan.
4. Or worst of all, give in to the kids and let them have their way when they whimper.

Four Useful Strategies for Parenting a Whiner 

1. Dramatically change the way you think: Whining comes from GOOD parenting; it does not mean you did something wrong.

2. Tell your child, “Whining is for your room.” Let them moan where you can’t hear it, but once they have calmed down, make sure they comply with your initial 'demand.' If they do not, then send them to their room again and repeat until they are willing to comply.

3. Use small, reasonable consequences. For example, "For every minute you whine at me, you are going to pay me 25 cents."

This 'monetary' forfeit may only work in a deeply consumer-based society where the child has a certain amount of 'disposable wealth,' like the US and the UK, but the principal of applying a 'loss' for unwanted behaviour is sound.

Keep any consequence simple, clear and short. Then no more talking, until the child changes its behaviour and complies.

There is No Negotiation and No Discussion allowed as this is simply another 'Testing' behaviour used by the child to take control of the situation and avoid doing what you want.

If you find this difficult, try avoiding eye contact with the child as well as not talking, this will help you stay stronger and stick to your goal.

4. You can also try using the age-old Counting Method from 1‐2‐3 for addressing the whining, but this should be a well understood way of correcting your child's unwanted behviour. It should be something you have practiced with your child from when they were very young.

If you want more information on correcting unwanted child behaviour and advice on sleep, bed-wetting and more serious childhood conditions, visit www.dream-angus.com

Wednesday, September 24, 2014

Children can be trained to recognise emotions

Children can using training to spot crucial cues on someone's emotional state, new research from the University of Lincoln, UK, has show.

Children can learn to better recognise other people's emotions through games which emphasise the significance of the eyes and the mouth in conveying feelings, new research has shown.

The study by cognitive neuroscientists at the University of Lincoln, UK, suggests that simple training programmes could help children better understand which expressive facial features offer the most important cues to other people's emotional state.

It is hoped the findings, published in the peer reviewed science journal PLOS ONE, could lead to new or improved interventions for children and adults who have difficulty recognising emotional states in others.

Dr Petra Pollux, a cognitive neuroscientist from the University of Lincoln's School of Psychology, said: "How we recognise and process facial expressions plays a big part in our social interaction skills."

"We've all experienced walking into a room, looking around and immediately understanding that something has happened, and that's because we're reading the expressions on people's faces."

"This ability to understand and read facial expressions is a crucial skill in development and begins at quite an early age."

"Generally, when we look at faces, we look at the eyes and the mouth, but with a definite bias towards the eyes."

"We wanted to investigate if there was a correlation between which parts of the face the children looked at and their ability to correctly pick up on the emotional state of the person in the image."

During the study nine-year-old children were shown images which conveyed varying levels of intensity of emotional expressions, from a small smile to a big grin, and asked to match it with the correct emotion. If they answered incorrectly, they were alerted by a tone.

Children and adults were not given any instructions about eye-movements, but over the four sessions learned that focusing more on the eyes offered the crucial clues they needed.

The images used in the study were digitally manipulated and showed happy, sad or fearful expressions.

An adult's ability to recognise emotions was also assessed and compared with children's, and in both cases, special eye tracking equipment was used to monitor their gaze pattern and determine which features of the face, such as the eyes, nose or mouth, they focused on most.

Children looked less often and for a shorter duration at the eyes, and more often and for longer at the mouth compared with adults.

Training for both adults and children increased the amount of time spent looking at the eyes, although for adults this was only for faces which showed a sad expression.

Children, however, showed a significant increase in the amount of time spent focused on the eyes of all three expressions after training, leading to more correct answers.

The images used in the final session were also replaced by new faces, meaning their abilities translated to different people, researchers said.

Dr Pollux added: "It's really useful to know that the way a child scans a face plays an important role in recognising emotions. This research could be used to develop mobile phone apps which turn this kind of training into a game."

Researches now hope that the findings will inform training programmes for people in need of a better understanding of recognising facial expressions, such as those with autism or other cognitive development problems.

More information: Pollux PML, Hall S, Guo K (2014) "Facial Expression Training Optimised Viewing Strategy in Children and Adults." PLOS ONE 9(8): e105418. DOI: 10.1371/journal.pone.0105418

Tuesday, September 23, 2014

Beat synchronization in preschoolers aids learning and reading skills

A team of researchers with Northwestern University in the U.S. has found that an ability to synchronize with a beat may be an indication of how well preschoolers will later do when developing reading skills.

In their paper published in Proceedings of the National Academy of Sciences, the team describes a study they undertook that involved testing for beat synchronization and sound recognition in preschoolers and what they found as a result.

Devising a test for reading aptitude prior to teaching children to read, it is believed, would help children of all levels learn better.

If a teacher knew beforehand that a child was going to have a reading disability, for example, that child could be placed into a program developed specifically for their needs, hopefully offering a better long term outcome.

Likewise, children with an exceptional aptitude for reading could be put into an accelerated program to prevent boredom.

Unfortunately, there is no such test, thus parents and teachers are left to discover a child's reading abilities on their own.

In this new effort, the researchers devised a study to find out if beat synchronicity skills might be used as the basis for such a test.

Reading specialists have suspected that there is a link between beat synchronization and both language and reading ability, reading and speech are both timing based after all.

To better understand that link the researchers arranged to test preschool volunteers.

In the first test, 35 children were given a toy drum and asked to beat it in time with an adult beating on a similar drum.

Those that could do it well were described as synchronizers, those that could not, as nonsyncronizers.

The same group of children then had electrodes pasted to their scalps to measure brain waves, as the researchers watched monitors, the children listened to sounds the researchers played, such as "da" and "ba" with no other sound, and then with background noise.

In studying the data, the researchers found that the children dubbed synchronizers in the first part of the experiment processed the played sounds with greater precision than did the nonsyncronizers.

Further tests revealed that the synchronizers did better on overall language abilities than the nonsyncronizers, which suggests that it might be possible to use the same process to test children as young as infants for later reading ability.

The researchers plan to continue monitoring the same children in the study for five years to see if their testing method is viable.

More information: Beat synchronization predicts neural speech encoding and reading readiness in preschoolers, Kali Woodruff Carr, PNAS, DOI: 10.1073/pnas.1406219111

Saturday, September 20, 2014

US Congressional Committee Hearing on the Science of Dyslexia

In an age of gridlock and choking polarization, the yesterday’s Congressional Committee Hearing on the Science of Dyslexia evoked the best qualities of US governmental process: bringing elected officials to the table with ordinary citizens in non-partisan dialogue to solve a major societal problem.

For a two hours in Rayburn room 2318 on Capitol Hill, there were no Democrats or Republicans, just people concerned about the prevalence of dyslexia in our nation’s children and the fact that millions of families are struggling, and convinced that something huge needs to be done to help these kids read, learn and thrive.

What made the event most remarkable was its emotional richness. As data points from the vast body of dyslexia science were shared by leading experts, tears flowed and laughter filled the air.

At one point, Committee Chairman Lamar Smith of Texas commented that he’d never heard such eruptions of applause and enthusiasm in a Congressional Hearing.

Best of all, the event was made accessible for everyone: its live webcast was recorded and archived; and all of the testimony was transcribed.

Here are several highlights.

Clicking on the speakers’ names will bring up a full transcript of their remarks:

Rep. Bill Cassidy of Louisiana gave some of the day’s most compelling and heart-wrenching testimony, pausing several times to wipe away tears and collect himself.

“A couple of years ago, my youngest daughter was diagnosed with dyslexia. Prompted by concerns about my daughter and my constituents’ children, I set out to learn as much as I could about dyslexia and was amazed at how much is known and yet, far too often, not incorporated into public policy and education. . ."

"If dyslexia is identified in elementary school and the appropriate resources are given to these children, America can produce more teachers, more scientists and more entrepreneurs.”

Brownley1Rep. Julia Brownley of California also shared personal perspectives as a parent.

“When my daughter Hannah struggled to learn to read, like any parent I was completely panicked about what to do next."

"It was Hannah’s dyslexia, and learning to navigate the school system, where I witnessed the good, the bad, and the ugly, that led me to public service. . ."

"This spring, Hannah received her Master’s degree in International Studies, and is now overseas saving the world with a NGO in Kenya, Africa."

"She speaks three languages, and she still misspells in all of them! I could not be prouder of her. But for every success story like Hannah, there are countless others who do not succeed.”

Sally1Dr. Sally Shaywitz of the Yale Center for Dyslexia and Creativity made a passionate plea to policy makers that now is the time to translate science into action.

“In dyslexia, remarkably in America, in the year 2014, we have not a knowledge gap but an action gap."

"We have the knowledge but it is not being put into policy and practice and far too many children and adults, too, are suffering needlessly."

"There is an epidemic of reading failure that we have the scientific evidence to treat effectively and we are not acknowledging or implementing it. . ."

"I cannot look into the face of one more child who has lost faith in himself and the world, I cannot look into the face of a child’s father who is desperately trying to hold back tears; I cannot hear once again about how a school told a mother, ‘we do not believe in dyslexia.’. . ."

"It is our hope that hearing the depth and extent of the scientific knowledge of dyslexia will alert policy makers to act and to act with a sense of urgency. ”

Max Brooks, an accomplished author and screenwriter, electrified Committee members and the gallery crowd with his personal account of living with dyslexia:

“For me, dyslexia was nearly as bad as the feelings of anxiety, shame, and low self-esteem that it caused."

"For me, ‘learned dependency’ was the real enemy, the self-narrative that ‘I can’t do this’ that can destroy children’s learning potential for the rest of their lives."

"That was ALMOST me. I’ve spent the last 30 years unlearning the lesson that dyslexia taught me, that society has no use for me. . ."

“A little awareness and flexible teaching methods could unlock unlimited potential in these kids who now think they’re losers."

"If we already have mandatory racial sensitivity training for our police, why not have mandatory dyslexia recognition training for our teachers?"

"It’s so simple, so easy, and when you look at all the other government programs designed to help citizens help themselves, it’s probably the least expensive.”

Persusasive testimony was also given by panelists Stacy Antie, a mother and parent advocate; Paul Eden, president of Landmark College; and Guinevere Eden, Director of the Center for the Study of Learning (CSL) and Professor, Department of Pediatrics, Georgetown University Medical Center.

Later on in a Q&A session with Committee lawmakers, Max Brooks revived his comment about making dyslexia training “a mandatory part of every teacher’s certificate,” instantly sparking whoops of applause from the gallery crowd, including many members of the Decoding Dyslexia movement.

And those Decoding Dyslexia members, from states as nearby as Virginia, New Jersey and Pennsylvania, and from as far away as Texas, graciously gathered for a photo op of their own before the day’s proceedings concluded.

After the Committee Hearing, attendeees and panelists enjoyed a great luncheon hosted by the National Center for Learning Disabilities, featuring a preview look at the new Understood.org initiative and a website that will launch later this month.

This was followed by speeches by an assortment of guests, including Hal Malchow, President of the International Dyslexia Association, Robbi Cooper of Decoding Dyslexia Texas, and Kristin Kane of Decoding Dyslexia Virginia.

What will be the net impact of a day like this on our nation’s dyslexic children and the parents and teachers who support them?

It’s hard to say, but there was enough knowledge, passion and experience gathered there on Capitol Hill to move mountains.

With so many diverse players assembled at the table, it brought to life the vivid slogan Learning Ally has embraced this year: Together It’s Possible.

All credit goes to Learning Ally for the content of this article.

Friday, September 12, 2014

ADHD: Medication plus parent training may help kids with aggression

Combining two medications with parent training appears to improve anger, irritability and violent tendencies in children whose attention-deficit/hyperactivity disorder (ADHD) is coupled with severe aggression, a new study suggests.

"Augmented" therapy that consists of stimulant and antipsychotic drugs, along with parent training in behavioural management techniques, was rated more effective by parents than "basic" therapy pairing only the stimulant and parent training, researchers found.

"An important finding of this study was that at the end of nine weeks, approximately half of all children receiving basic therapy were still rated by their parents as being impaired... with symptoms interfering with school or social functioning," said study author Kenneth Gadow, a professor of psychiatry at Stony Brook University in New York.

"In the augmented group receiving three interventions for aggression, about one-quarter still, at the end of nine weeks, were rated by their parents as being impaired, and that suggests, even with highly effective therapies, that many of these children still have unmet treatment needs" " he added.

The drugs used in the study, published in the September issue of the Journal of the American Academy of Child and Adolescent Psychiatry, included the widely prescribed ADHD stimulant Concerta (methylphenidate) and the antipsychotic Risperdal (risperidone).

Approximately 11 percent of American children aged 4 to 17 have been diagnosed with ADHD, which includes symptoms such as impulsivity, hyperactivity, and difficulty focusing and controlling behavior, according to the U.S. Centers for Disease Control and Prevention.

As many as half of children with ADHD also display significant, disruptive aggression, according to an editorial accompanying the new research.

"This is very common among kids with ADHD, but unfortunately it complicates the picture for treatment," said Erin Schoenfelder, a clinical psychologist at Seattle Children's Hospital and assistant professor of psychiatry and behavioural health at University of Washington.

"It really is staggeringly high."

In the new research, Gadow and his colleagues divided a group of nearly 170 children aged 6 to 12 with ADHD and aggression problems into two treatment groups, basic and augmented.

The basic group received Concerta and their parents underwent behavioral management training.

The augmented group received Concerta and parental training as well, but also took the antipsychotic Risperdal. Both groups were followed for nine weeks.

While both groups of children displayed marked reduction in symptoms, improvement ratings varied depending on whether parents or teachers were making the assessment.

Parents reported that children on augmented therapy were less likely to be impaired socially or academically by their anger and irritability than children on basic therapy.

On the other hand, teachers found few differences in these measures.

Instead, teachers of those on augmented therapy reported significant drops in ADHD symptoms, especially impulsiveness, compared with teachers of children on basic therapy.

Gadow and Schoenfelder agreed that the conflicting parent-teacher ratings demonstrate a familiar concept: that children's behaviours vary in different settings, whether or not they have ADHD.

"Just like adults, they adapt their behaviours to be more appropriate for the setting they're in," Gadow said.

"People do differ, however, in their ability to modify their behaviour from one setting to the next, and some children are much more variable [in this regard]."

Schoenfelder said long-term evidence is needed indicating that combining Concerta and Risperdal is safe in children, but "it appears from this study that the combination was well-tolerated and something practitioners could [adjust the dosage of] effectively."

"Folks trying this type of treatment should have close monitoring," she added. "This is a starting point. It's a combination doctors may try when they see this blend of aggressive and hyperactive behaviours. It certainly will require adjustment . . . but it's exciting to find something helpful for a significant proportion of the kids studied."

The study authors pointed out that their findings only apply to children with ADHD who exhibit severe irritability and peer aggression.

They noted that the study's findings are not an indication of the ADHD population as a whole.

More Information: "Risperidone Added to Parent Training and Stimulant Medication: Effects on Attention-Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, and Peer Aggression" http://www.jaacap.com/article/S0890-8567(14)00369-4/abstract

Thursday, August 21, 2014

Children with autism have extra synapses in brain

In a study of brains from children with autism, researchers found that autistic brains did not undergo normal pruning during childhood and adolescence. 

The images show representative neurons from autistic (left) and control (right) brains; the spines on the neurons indicate the location of synapses.

Credit: Guomei Tang, PhD and Mark S. Sonders, PhD/Columbia University Medical Center

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain "pruning" process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC).

Because synapses are the points where neurons connect and communicate with each other, the excessive synapses may have profound effects on how the brain functions.

The study was published in the August 21 online issue of the journal Neuron.

A drug that restores normal synaptic pruning can improve autistic-like behaviors in mice, the researchers found, even when the drug is given after the behaviours have appeared.

"This is an important finding that could lead to a novel and much-needed therapeutic strategy for autism," said Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUMC and director of New York State Psychiatric Institute, who was not involved in the study.

Although the drug, rapamycin, has side effects that may preclude its use in people with autism, "the fact that we can see changes in behaviour suggests that autism may still be treatable after a child is diagnosed, if we can find a better drug," said the study's senior investigator, David Sulzer, PhD, professor of neurobiology in the Departments of Psychiatry, Neurology, and Pharmacology at CUMC.

David Sulzer
During normal brain development, a burst of synapse formation occurs in infancy, particularly in the cortex, a region involved in autistic behaviours; pruning eliminates about half of these cortical synapses by late adolescence.

Synapses are known to be affected by many genes linked to autism, and some researchers have hypothesized that people with autism may have more synapses.

To test this hypothesis, co-author Guomei Tang, PhD, assistant professor of neurology at CUMC, examined brains from children with autism who had died from other causes.

Thirteen brains came from children ages two to 9, and thirteen brains came from children ages 13 to 20. Twenty-two brains from children without autism were also examined for comparison.

Dr. Tang measured synapse density in a small section of tissue in each brain by counting the number of tiny spines that branch from these cortical neurons; each spine connects with another neuron via a synapse.

By late childhood, she found, spine density had dropped by about half in the control brains, but by only 16 percent in the brains from autism patients.

"It's the first time that anyone has looked for, and seen, a lack of pruning during development of children with autism," Dr. Sulzer said, "although lower numbers of synapses in some brain areas have been detected in brains from older patients and in mice with autistic-like behaviours."


Clues to what caused the pruning defect were also found in the patients' brains; the autistic children's brain cells were filled with old and damaged parts and were very deficient in a degradation pathway known as "autophagy."

Cells use autophagy (a term from the Greek for self-eating) to degrade their own components. Using mouse models of autism, the researchers traced the pruning defect to a protein called mTOR.

When mTOR is overactive, they found, brain cells lose much of their "self-eating" ability and without this ability, the brains of the mice were pruned poorly and contained excess synapses.

"While people usually think of learning as requiring formation of new synapses, "Dr. Sulzer says, "the removal of inappropriate synapses may be just as important."

The researchers could restore normal autophagy and synaptic pruning, and reverse autistic-like behaviors in the mice, by administering rapamycin, a drug that inhibits mTOR.

The drug was effective even when administered to the mice after they developed the behaviors, suggesting that such an approach may be used to treat patients even after the disorder has been diagnosed.

Because large amounts of overactive mTOR were also found in almost all of the brains of the autism patients, the same processes may occur in children with autism.

"What's remarkable about the findings," said Dr. Sulzer, "is that hundreds of genes have been linked to autism, but almost all of our human subjects had overactive mTOR and decreased autophagy, and all appear to have a lack of normal synaptic pruning.

This says that many, perhaps the majority, of genes may converge onto this mTOR/autophagy pathway, the same way that many tributaries all lead into the Mississippi River.

Overactive mTOR and reduced autophagy, by blocking normal synaptic pruning that may underlie learning appropriate behaviour, may be a unifying feature of autism."

Alan Packer, PhD, senior scientist at the Simons Foundation, which funded the research, said the study is an important step forward in understanding what's happening in the brains of people with autism.

"The current view is that autism is heterogeneous, with potentially hundreds of genes that can contribute."

"That's a very wide spectrum, so the goal now is to understand how those hundreds of genes cluster together into a smaller number of pathways; that will give us better clues to potential treatments," he said.

"The mTOR pathway certainly looks like one of these pathways. It is possible that screening for mTOR and autophagic activity will provide a means to diagnose some features of autism, and normalizing these pathways might help to treat synaptic dysfunction and treat the disease."

Journal Reference: 
Guomei Tang, Kathryn Gudsnuk, Sheng-Han Kuo, Marisa L. Cotrina, Gorazd Rosoklija, Alexander Sosunov, Mark S. Sonders, Ellen Kanter, Candace Castagna, Ai Yamamoto, Zhenyu Yue, Ottavio Arancio, Bradley S. Peterson, Frances Champagne, Andrew J. Dwork, James Goldman, David Sulzer. "Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits." Neuron, 2014; DOI: 10.1016/j.neuron.2014.07.040

ADHD children make poor decisions due to less differentiated learning processes

Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most common psychiatric disorders among school children. Pupils with ADHD often make poorer decisions than their unaffected classmates.

Researchers from the University of Zurich now discovered that different learning and decision-making mechanisms are responsible for these behaviors, and localized the underlying impairments in the brain.

Which shirt do we put on in the morning? Do we drive to work or take the train? From which takeaway joint do we want to buy lunch?

We make hundreds of different decisions every day. Even if these often only have a minimal impact, it is extremely important for our long-term personal development to make decisions that are as optimal as possible.

People with ADHD often find this difficult, however. They are known to make impulsive decisions, often choosing options which bring a prompt but smaller reward instead of making a choice that yields a greater reward later on down the line.

Researchers from the University Clinics for Child and Adolescent Psychiatry, University of Zurich, now reveal that different decision-making processes are responsible for such suboptimal choices and that these take place in the middle of the frontal lobe.

Mathematical models help to understand the decision-making processes
In the study, the decision-making processes in 40 young people with and without ADHD were examined.

Lying in a functional magnetic resonance imaging (fMRI) scanner to record the brain activity, the participants played a game where they had to learn which of two images carried more frequent rewards.

To understand the impaired mechanisms of participants with ADHD better, learning algorithms which originally stemmed from the field of artificial intelligence were used to evaluate the data.

These mathematical models help to understand the precise learning and decision-making mechanisms better.

"We were able to demonstrate that young people with ADHD do not inherently have difficulties in learning new information; instead, they evidently use less differentiated learning patterns, which is presumably why sub-optimal decisions are often made", says first author Tobias Hauser.

Multimodal imaging affords glimpses inside the brain
To study the brain processes that triggered these impairments, the authors used multimodal imaging methods, where the participants were examined using a combined measurement of functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to record the electrical activity and the blood flow in the brain.

It became apparent that participants with ADHD exhibit an altered functioning in the medial prefrontal cortex, a region in the middle of the frontal lobe.

This part of the brain is heavily involved in decision-making processes, especially if you have to choose between several options, and in learning from errors.

Although a change in activity in this region was already discovered in other contexts for ADHD, the Zurich researchers were now also able to pinpoint the precise moment of this impairment, which already occurred less than half a second after a feedback, i.e. at a very early stage.

Psychologist Tobias Hauser, who is now researching at the Wellcome Trust Centre for Neuroimaging, University College London, is convinced that the results fundamentally improve our understanding of the mechanisms of impaired decision-making behaviour in people with ADHD.

The next step will be to study the brain messenger substances. "If our findings are confirmed, they will provide key clues as to how we might be able to design therapeutic interventions in future," explains Hauser.

More information: Tobias U. Hauser, Reto Iannaccone, Juliane Ball, Christoph Mathys, Daniel Brandeis, Susanne Walitza & Silvia Brem: Role of Medial Prefrontal "Cortex in Impaired Decision Making in Juvenile Attention-Deficit/Hyperactivity Disorder," in: JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.1093

Monday, August 18, 2014

The boundaries of reading apps for children

A series of binary discussions has been plaguing early reading instruction for quite some time now: phonics versus whole language, reading for pleasure versus reading for learning, digital versus paper books and it seems that there is a new tug-of-war on the educational horizon: spritzing versus slow reading.

Spritz is a recently developed programme that brings speed-reading to the untrained eye. Its makers claim that users can ultimately read 1,000 words per minute.

Their goal is to have 15% of the world's texts available in Spritz format by 2016.

But a message is coming from the other direction too. Those who revere and often romanticise printed books argue that we need to slow down.

They warn that the digital age has made us shallow readers who flit from text to text without taking anything in.

We have a clear conflict here. On one hand, lots of people want to read faster, especially now that there is more to read out there than at any other time in human history.

On the other hand, we hear that children in the digital age do not read in depth and the often cited culprit is the device in their hand – the technology that distracts them from picking up a good book.

Is a middle ground possible?

Reading and writing always come hand-in-hand. If readers whizz through rather than engage with texts, this will ultimately be reflected in the type of texts made available to them.

Spritz certainly responds to the zeitgeist to read fast in order to cope in a text-saturated era. You can also see this tendency in the proliferation of listicles on news websites and contents pages that tell you how long it will take you to read an article.

Some say that the only way to cope with large email volumes, is to binge-read our inboxes. Spritz could be thus seen as another invention that panders to our growing tendency to read more but in less depth.

At the same time, readers, be they young or old,need to be given time to pause and think with the author of a text.

Slow reading is, for many, synonymous with deep reading and reading for learning and there are in fact technological developments happening to help readers improve their deep reading, almost the antidote to Spritz.

There are reading annotation systems with built-in interactive discussion to help readers, students in particular, to better understand what they are reading.

These slow them down in their reading by asking them questions or prompting them to pause and take notes.

Similarly for younger readers, there are read-to-learn apps that explain vocabulary and thus help with reading comprehension.

So which approach is better for the contemporary reader? We can now whizz through every page on the internet by installing Spritzlet on our web browser.

It may not be long until slow reading widgets will become available to help us highlight information in onscreen texts, underline unfamiliar words, unpick abstract metaphors and provide links to facts.

In thinking about how to teach children to read effectively in digital age, we need to stop thinking in terms of slow and fast.

There is a difference between reading an email or a chemistry textbook or a novel. We use different reading formats for different contents, and different contents & formats for different purposes.

These different purposes come with different personal investments and hence different reading techniques.

There is already a disturbing disconnect between the content and format of reading happening in schools and outside the classrooms. Let's not increase this gap with another fictitious dichotomy.

Tuesday, August 5, 2014

Children with Autism: Blood-oxytocin levels in normal range

Spacefilling model of oxytocin. Created using ACD/ChemSketch 8.0, ACD/3D Viewer and The GIMP. 

Credit: Wikipedia.

Autism does not appear to be solely caused by a deficiency of oxytocin, but the hormone's universal ability to boost social function may prove useful in treating a subset of children with the developmental disorder, according to new findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford.

Low levels of oxytocin, a hormone involved in social functioning, have for years been suspected of causing autism. Prior research seeking a link has produced mixed results.

Now, in the largest-ever study to test the purported connection, the range of blood oxytocin levels has been shown to be the same in children with autism as that observed in two comparison groups: children with autistic siblings and children without autistic siblings.

In other words, similar numbers of children with low, medium and high oxytocin levels were found in all three groups.

A paper describing the new findings will be published online Aug. 4 in Proceedings of the National Academy of Sciences (PNAS).

Although autism was not directly linked to oxytocin deficiency, the Stanford team found that higher oxytocin levels were linked to better social functioning in all groups.

All children with autism have social deficits, but in the study these deficits were worst in those with the lowest blood oxytocin and mildest in those with the highest oxytocin.

In the comparison groups, children's social skills also fell across a range that correlated to their oxytocin levels.

"Oxytocin appears to be a universal regulator of social functioning in humans," said Karen Parker, PhD, assistant professor of psychiatry and behavioural sciences and the lead author of the study.

"That encompasses both typically developing children as well as those with the severe social deficits we see in children with autism."

Autism is a developmental disorder that affects 1 of every 68 children in the United States. It is characterised by social and communication deficits, repetitive behaviours and sensory problems.

The new study included 79 children with autism, 52 of their unaffected siblings and 62 unrelated children without autism. All of the children were between the ages of 3 and 12.

"It didn't matter if you were a typically developing child, a sibling or an individual with autism: Your social ability was related to a certain extent to your oxytocin levels, which is very different from what people have speculated," said Antonio Hardan, MD, professor of psychiatry and behavioural sciences and the study's senior author.

Hardan is a child and adolescent psychiatrist who treats children with autism at the hospital.

"The previous hypotheses saying that low oxytocin was linked to autism were maybe a little bit simplistic," he said.

"It's much more complex: Oxytocin is a vulnerability factor that has to be accounted for, but it's not the only thing leading to the development of autism."

The researchers caution, however, that blood oxytocin measurements may be different than oxytocin levels in the cerebrospinal fluid bathing the brain, which they did not measure.

In addition to examining blood oxytocin levels, the researchers examined the importance of small variations in the gene coding for the oxytocin receptor.

Certain receptor variants were correlated to higher scores on standard tests of social ability, the study found.

The team also discovered that blood levels of oxytocin are highly heritable: The levels are influenced by inheritance to about the same degree as adult height, which is often described as being strongly influenced by genetics.

"What our study hints at is that social function may be heritable in families," Parker said.

The study will help to guide future research to determine whether oxytocin is a useful autism treatment.

The study's findings suggest that some children with autism, such as the subset of kids with autism who have naturally low oxytocin levels, or those with oxytocin receptor gene variants associated with worse social functioning, might benefit most from oxytocin-like drugs.

"Autism is so heterogeneous," Parker said. "If we can identify biomarkers that help us identify the patients most likely to benefit from a specific therapy, we expect that will be very useful."

More information: "Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder," by Karen J. Parker et al. PNAS, www.pnas.org/cgi/doi/10.1073/pnas.1402236111

Tuesday, June 3, 2014

Children with autism have elevated levels of steroid hormones in the womb

Scientists from the University of Cambridge and the Statens Serum Institute in Copenhagen, Denmark have discovered that children who later develop autism are exposed to elevated levels of steroid hormones (for example testosterone, progesterone and cortisol) in the womb.

The finding may help explain why autism is more common in males than females, but should not be used to screen for the condition.

Funded by the Medical Research Council (MRC), the results are published today in the journal Molecular Psychiatry.

The team, led by Professor Simon Baron-Cohen and Dr Michael Lombardo in Cambridge and Professor Bent Nørgaard-Pedersen in Denmark, utilized approximately 19,500 amniotic fluid samples stored in a Danish biobank from individuals born between 1993-1999.

Amniotic fluid surrounds the baby in the womb during pregnancy and is collected when some women choose to have an amniocentesis around 15-16 weeks of pregnancy.

This coincides with a critical period for early brain development and sexual differentiation, and thus allows scientists access into this important window in fetal development.

The researchers identified amniotic fluid samples from 128 males later diagnosed with an autism spectrum condition and matched these up with information from a central register of all psychiatric diagnoses in Denmark.

Within the amniotic fluid the researchers looked at 4 key 'sex steroid' hormones that are each synthesized, step-by-step from the preceding one, in the 'Δ4 sex steroid' pathway: progesterone, 17α-hydroxy-progesterone, androstenedione and testosterone.

They also tested the steroid hormone cortisol that lies outside this pathway. The researchers found that levels of all steroid hormones were highly associated with each other and most importantly, that the autism group on average had higher levels of all steroid hormones, compared to a typically developing male comparison group.

Professor Baron-Cohen said: "This is one of the earliest non-genetic biomarkers that has been identified in children who go on to develop autism."

"We previously knew that elevated prenatal testosterone is associated with slower social and language development, better attention to detail, and more autistic traits."

"Now, for the first time, we have also shown that these steroid hormones are elevated in children clinically diagnosed with autism."

"Because some of these hormones are produced in much higher quantities in males than in females, this may help us explain why autism is more common in males."

He added: "These new results are particularly striking because they are found across all the subgroups on the autism spectrum, for the first time uniting those with Asperger Syndrome, classic autism, or Pervasive Developmental Disorder Not-Otherwise-Specified. We now want to test if the same finding is found in females with autism."

Dr Michael Lombardo said: "This result potentially has very important implications about the early biological mechanisms that alter brain development in autism and also pinpoints an important window in fetal development when such mechanisms exert their effects."

Steroid hormones are particularly important because they exert influence on the process of how instructions in the genetic code are translated into building proteins.

The researchers believe that altering this process during periods when the building blocks for the brain are being laid down may be particularly important in explaining how genetic risk factors for autism get expressed.

Dr Lombardo adds: "Our discovery here meshes nicely with other recent findings that highlight the prenatal period around 15 weeks gestation as a key period when important genetic risk mechanisms for autism are working together to be expressed in the developing brain."

Professor Baron-Cohen said: "These results should not be taken as a reason to jump to steroid hormone blockers as a treatment as this could have unwanted side effects and may have little to no effect in changing the potentially permanent effects that fetal steroid hormones exert during the early foundational stages of brain development."

He cautioned further: "Nor should these results be taken as a promising prenatal screening test. There is considerable overlap between the groups and our findings showed differences found at an average group level, rather than at the level of accurately predicting diagnosis for individuals."

"The value of the new results lies in identifying key biological mechanisms during fetal development that could play important roles in atypical brain development in autism."

Monday, April 21, 2014

ADHD: Language problems common in children with ADHD

Children who have attention-deficit/hyperactivity disorder are nearly three times more likely to have language problems than kids without ADHD, according to new research.

And those language difficulties can have far-reaching academic consequences, the study found.

The study, published online April 21 in Pediatrics, looked at 6- to 8-year-olds with and without ADHD in Australia.

"We found that 40 percent of children in the ADHD group had language problems, compared to 17 percent of children in the 'control' group," said Emma Sciberras, a clinical psychologist and post-doctoral research fellow at the Murdoch Children's Research Institute in Victoria, Australia.

"Rates of language problems were similar in boys and girls with ADHD," she added.

Emma Sciberras
Children with ADHD commonly have trouble with school performance and social functioning.

The impact that language problems might have on these factors hasn't been well-studied, the study authors noted.

"The differences in academic functioning between children with ADHD and language problems, compared to those with ADHD alone, were quite large and clinically meaningful," said Sciberras.

Language problems refer to spoken language—both receptive and expressive language. Receptive language is the ability to listen and understand what's being said; expressive is the ability to speak and be understood.

In a separate study in the same issue of the journal, Sciberras and her colleagues looked at almost 400 children with ADHD, aged 5 to 13, and found almost two-thirds had one or more anxiety disorders.

When children with ADHD had two or more anxiety disorders—this was true for one-third of the kids—their quality of life, behavior and daily functioning suffered, the researchers said.

"It is very common for children with ADHD to experience additional difficulties," said Sciberras. "Both of these studies demonstrate that the additional difficulties that go along with ADHD, in this case anxiety and language problems, can make daily functioning even harder for children with ADHD."

The language study included 179 children diagnosed with ADHD and 212 without the attention disorder. Fewer than half of the children with ADHD were taking medications to help control their symptoms.

After adjusting for sociodemographic factors and other conditions, such as autism spectrum disorders, the researchers found that the risk of language problems was 2.8 times higher in children with ADHD.

When the researchers looked at how those language problems affected school work, they found lower math, reading and academic scores.

However, the researchers didn't find that language problems had an impact on social functioning.

"We were surprised that language problems were not associated with poorer social functioning for children with ADHD," Sciberras said.

"It could be that children with ADHD are already experiencing poorer social functioning due to other factors including their ADHD symptoms or other associated difficulties."

However, Sciberras cautioned that language troubles might become more problematic as these kids get older because social relationships get more complex with age.

One outside expert said the study is a good reminder for parents and physicians.

Bradley Berg
"If a child has ADHD and they're struggling in school, even though their ADHD symptoms are well-controlled, in addition to getting tested for learning disabilities, they should also be looked at for language difficulties as well. And that's not something we always think of," said Dr. Bradley Berg, medical director of McLane Children's Pediatrics at Baylor Scott & White Healthcare in Round Rock, Texas.

Whether speech-language interventions will help the youngsters with ADHD isn't clear, however.

Berg also pointed out that this issue is a "chicken-and-egg" problem.

He said "We don't know if these kids have;
  • a language disorder that's causing them to not understand what's going on at school 
      • and that's making them restless and fidgety because they're bored
  • Or do they have ADHD and that's causing difficulty understanding the language. 
  • Or is there something going on in an area of the brain that creates both of these problems?

It's possible that the findings from this Australian study might not translate to a U.S. population.

For one thing, medication trends might differ, Berg said. For children with ADHD who also suffer anxiety, Sciberras said medications might help, and a type of psychotherapy called cognitive behavioral therapy could also be useful.

The researchers are currently conducting a study to treat anxiety in children with ADHD.

"If parents are concerned that their child with ADHD has anxiety, language or any other additional difficulties that are not currently being managed, we encourage them to discuss their concerns with their child's treating clinician," she said.

Tuesday, April 15, 2014

Autism: Parents advised to get a dog

Many families face the decision of whether to get a dog.

For families of children with autism, the decision can be even more challenging.

Now, a University of Missouri researcher has studied dog ownership decisions in families of children with autism and found, regardless of whether they owned dogs, the parents reported the benefits of dog ownership included companionship, stress relief and opportunities for their children to learn responsibility.

"Children with autism spectrum disorders often struggle with interacting with others, which can make it difficult for them to form friendships," said Gretchen Carlisle, a research fellow at the Research Center for Human-Animal Interaction (ReCHAI) in the MU College of Veterinary Medicine.

"Children with autism may especially benefit from interacting with dogs, which can provide unconditional, nonjudgmental love and companionship to the children."

Carlisle interviewed 70 parents of children with autism. Nearly two-thirds of the parents in the study owned dogs, and of those parents, 94 percent reported their children with autism were bonded to their dogs.

Even in families without dogs, 70 percent of parents said their children with autism liked dogs.

Many dog-owning parents said they specifically chose to get dogs because of the perceived benefits to their children with autism, Carlisle said.

"Dogs can help children with autism by acting as a social lubricant," Carlisle said. "For example, children with autism may find it difficult to interact with other neighbourhood children."

"If the children with autism invite their peers to play with their dogs, then the dogs can serve as bridges that help the children with autism communicate with their peers."

Parents of children with autism should consider their children's sensitivities carefully when choosing a dog in order to ensure a good match between pet and child, Carlisle said.

"Bringing a dog into any family is a big step, but for families of children with autism, getting a dog should be a decision that's taken very seriously," Carlisle said.

"If a child with autism is sensitive to loud noises, choosing a dog that is likely to bark will not provide the best match for the child and the family."

"If the child has touch sensitivities, perhaps a dog with a softer coat, such as a poodle, would be better than a dog with a wiry or rough coat, such as a terrier."

Carlisle recommends parents involve their children with autism when choosing a dog.

"Many children with autism know the qualities they want in a dog," Carlisle said. "If parents could involve their kids in choosing dogs for their families, it may be more likely the children will have positive experiences with the animals when they are brought home."

Although her study only addressed dog ownership among families affected by autism, Carlisle said dogs might not be the best pet for every child with autism.

"If you know one child with autism, you know one child with autism," Carlisle said. "Dogs may be best for some families, although other pets such as cats, horses or rabbits might be better suited to other children with autism and their particular sensitivities and interests."

"This research adds scientific credibility to the benefits of human-animal interaction," said Rebecca Johnson, a professor at the MU College of Veterinary Medicine, director of ReCHAI, and the Millsap Professor of Gerontological Nursing in the MU Sinclair School of Nursing.

"This research helps us understand the role of companion animals in improving the lives of children with autism and helps health professionals learn how to best guide families in choosing pets for their families."

The study, "Pet Dog Ownership Decisions for Parents of Children With Autism Spectrum Disorder," was published in the Journal of Pediatric Nursing earlier this year.

Tuesday, April 1, 2014

Bullying affects most Adolescents, Popularity Increases the Risk of Getting Bullied

Bullying affects more than just those children who are seen to be isolated and marginalised, according to sociologists.

In fact, researchers have found that the 'popular' students are affected and may actually suffer more from a single act of social aggression.

"We did find that students who are isolated do get bullied," said Diane Felmlee, professor of sociology, Penn State.

Diane Felmlee
"However, for most students, the likelihood of being targeted by aggressive acts increases as a student becomes more popular, with the exception of those at the very top."

In a study of students and their friendship networks in 19 North Carolina schools, the researchers found that the risk of being bullied drops dramatically only for the adolescents in the top five percent of the school's social strata.

Bullying may be a tactical form of aggression, according to the researchers, who report their findings in the current issue of American Sociological Review (pdf).

Young people who are attempting to climb in status may increase their risk of victimization.

Robert Faris
"When youth are vying for status, they probably gain little from attacking students who are already marginalised, in fact, it might backfire," said Felmlee, who worked with Robert Faris, associate professor, University of California Davis.

"But, if adolescents put down someone who is trying to be a leader in their group, or who constitutes a threat to their status, then there is a lot more to be gained."

Faris and Felmlee also found that girls are more likely to be victims of both male and female bullies. Girls who date are at increased risk of physical violence.

"Girls may pose particular threats to other female students' social standing and represent potential rivals when it comes to securing a boyfriend," said Felmlee.

"For boys, girls who date represent rewarding, often popular and relatively easy targets who are unlikely to retaliate physically."

Students who have an aggressive friend tend to avoid being victimized. This may be further evidence that bullying is rarely an individual act, but associated with how friends establish and maintain hierarchies by protecting their own, according to the researchers.

There are serious costs associated with bullying over time, Felmlee said. Victims suffer elevated levels of anxiety, depression and anger. They tend to develop negative feelings about their schools, as well.

Bullying's detrimental effects can be even more pronounced among relatively popular students, according to the researchers.

Higher status students experienced significantly larger increases in depression, anxiety and anger than low-status students.

The friendships of these students also deteriorated.

"The effects of social aggression were magnified by the student's friendship status," said Felmlee.

"It may be that the kids who are extremely popular and rarely victimized had farther to fall than those more accustomed to being a target, so, although socially vulnerable youth suffer significantly from frequent harassment, more central victims of bullying, those who may be 'hidden in plain sight' face serious consequences."

The researchers examined data from the Context of Adolescent Substance Use study, which surveyed about 4,200 middle and high school students twice during the school year.

The surveys included questions on serious verbal and physical harassment, but did not include minor incidents, such as playful teasing.

The students were asked to provide information about their friendships, as well as information about students whom they believe they harassed and about those who they believe harassed them.

Tuesday, March 18, 2014

Parenting: Feeding Issues in childhood

Helping children learn to eat well can sometimes be a challenge. 

Some children happily eat whatever is put in front of them while others seem to eat like birds and exist more on air than food.

A new study by a researcher at the University of Colorado School of Medicine shows that parents influence how much children eat more than they may think.

In this collaborative study between the CU School of Medicine, Baylor College of Medicine and University of Alabama Birmingham, researchers observed normal, everyday mealtimes in the homes of 145 parents and their preschoolers recruited from a Head Start program in the Houston area.

They investigated the relationships between how much parents served themselves at mealtime, the amounts of foods they served to their children and how much children ate at dinner time.

The results revealed that parents served children very similar amounts to those they gave themselves and that the amounts children were served strongly predicted the amounts they ate.

For some children, this resulted in the consumption of adult-sized portions.

"The good news," said Susan Johnson, PhD, professor of pediatrics at the CU School of Medicine and a lead investigator for the study, "is that parents influence their children much more than they may feel they do."

"The challenge remains as to how to encourage children to consume a healthy diet and to eat amounts that help them grow appropriately."

"Clearly, family habits and behaviours are both incredibly important in this regard."

Johnson suggests paying attention to the portions offered to children and for parents to ensure that they offer child-sized portions of healthy foods.

Prompting children to eat according to their feelings of hunger and fullness, rather than parents deciding how much is enough, also is an important step towards promoting healthy eating and growth.

This study will be published in the April 2014 issue of The American Journal of Clinical Nutrition.

More Information: 'Portion sizes for children are predicted by parental characteristics and the amounts parents serve themselves' Susan L Johnson, et al., Am J Clin Nutr April 2014 ajcn.078311 - doi: 10.3945/​ajcn.113.078311