Brain's Lateral Prefrontal Cortex: Images help predict how smart you are

"There is evidence that the lateral prefrontal cortex is the brain region that 'remembers' (maintains) the goals and instructions that help you keep doing what is needed when you’re working on a task," says Michael Cole. 

"So it makes sense that having this region communicating effectively with other regions (the 'perceivers' and ‘doers’ of the brain) would help you to accomplish tasks intelligently." 

(Credit: Michael Cole/WUSTL)

As science has long suspected, overall brain size matters somewhat, accounting for about 6.7 percent of individual variation in intelligence.

More recent research has pinpointed the brain’s lateral prefrontal cortex, a region just behind the temple, as a critical hub for high-level mental processing, with activity levels there predicting another five percent of variation in individual intelligence.

Now, new research from Washington University in St. Louis suggests that another 10 percent of individual differences in intelligence can be explained by the strength of neural pathways connecting the left lateral prefrontal cortex to the rest of the brain.

Published in the Journal of Neuroscience, the findings establish “global brain connectivity” as a new approach for understanding human intelligence.

“Our research shows that connectivity with a particular part of the prefrontal cortex can predict how intelligent someone is,” suggests lead author Michael W. Cole, a postdoctoral research fellow in cognitive neuroscience.

The study is the first to provide compelling evidence that neural connections between the lateral prefrontal cortex and the rest of the brain make a unique and powerful contribution to the cognitive processing underlying human intelligence, says Cole, whose research focuses on discovering the cognitive and neural mechanisms that make human behaviour uniquely flexible and intelligent.

“This study suggests that part of what it means to be intelligent is having a lateral prefrontal cortex that does its job well; and part of what that means is that it can effectively communicate with the rest of the brain,” says study co-author Todd Braver, professor of psychology in Arts & Sciences and of neuroscience and radiology in the School of Medicine.

Braver is also a co-director of the Cognitive Control and Psychopathology Lab, where the research was conducted.

Read the full article at  Futurity.org or at Washington University

Let Go of Unachievablle Goals and be Happier

Reaching for the Moon? People who let go of unachievable old goals have a better quality of life, McGill University researchers have discovered. The discovery was made when they were studying data of breast cancer patients.

Researchers had studied 176 breast cancer survivors between the ages of 28 and 79. Self-reports of the individual's capacity to adjust their goals were measured at the start of the study. At the same time, researchers measured self-report of physical activity, sedentary activity, emotional well-being, and daily physical symptoms such as nausea and pain.

Three months later, they took a look at another round of self-reports. The study found that goal reengagement (being able to set new goals) was associated with more physical activity, increased emotional well-being and fewer physical symptoms. In addition, breast cancer survivors who were able to let go of old goals and to find new ones were less sedentary, which contributed to improved well-being. These findings support earlier research showing that goal adjustment can influence better well-being and health.

"By engaging in new goals a person can reduce the distress that arises from the desire to attain the unattainable, while continuing to derive a sense of purpose in life by finding other pursuits of value," said Carsten Wrosch, researchers at Concordia University's Department of Psychology and Centre for Research in Human Development. "Abandoning old goals allows someone to invest sufficient time and energy in effectively addressing their new realities."

Researchers have also suggested that breast cancer survivors should engage in at least 150 minutes of moderate to vigorous-intensity physical activity every week to gain health benefits.

"It is safe, feasible and effective for enhancing well-being and health among breast cancer survivors," said Catherine Sabiston, researcher at the McGill University. "Unfortunately, few survivors are engaging in the recommended levels of activity."

"Our research reveals that the capacity to adjust goals plays a pivotal role in facilitating not only high physical activity but also low sedentary activity and thereby contributing to overall improved well-being," said Wrosch. "Given that it is possible to influence adjustment to specific goals; it may be beneficial to integrate goal adjustment processes into clinical practice."